https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Prevalence of arthritis according to age, sex and socioeconomic status in six low and middle income countries: analysis of data from the World Health Organization study on global AGEing and adult health (SAGE) Wave 1 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30810 Wed 23 Feb 2022 16:04:14 AEDT ]]> Using population health data to measure healthcare costs of arthritis for Australian women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17202 Wed 21 Sep 2016 11:42:52 AEST ]]> PAIN - Novel targets and new technologies (editorial) https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19629 Wed 11 Apr 2018 16:52:46 AEST ]]> The relative importance of psychosocial factors in arthritis: findings from 10,509 Australian women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15663 Wed 11 Apr 2018 16:06:46 AEST ]]> The profile of pain in older women with arthritis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22746 Wed 11 Apr 2018 14:41:58 AEST ]]> Discordance between self-reported arthritis and musculoskeletal signs and symptoms in older women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29484 Wed 11 Apr 2018 13:13:28 AEST ]]> Workforce participation patterns over the life course and the association with chronic diseases – a gendered approach https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22323 Wed 11 Apr 2018 11:25:11 AEST ]]> When life's a pain: perceived stress and psychosocial factors in women with arthritis transitioning from midlife to older age https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13381 Wed 11 Apr 2018 09:54:43 AEST ]]> The influence of perceived stress on the onset of arthritis in women: findings from the Australian longitudinal study on women's health https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18227 Wed 11 Apr 2018 09:14:20 AEST ]]> How is the experience of pain measured in older, community-dwelling people with osteoarthritis? A systematic review of the literature https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28078 Wed 04 Sep 2019 10:40:20 AEST ]]> The prevalence and cross-sectional associations of neuropathic-like pain among older, community-dwelling women with arthritis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28077 Wed 04 Sep 2019 10:27:41 AEST ]]> Topical loperamide-encapsulated liposomal gel increases the severity of inflammation and accelerates disease progression in the adjuvant-induced model of experimental rheumatoid arthritis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33962 Wed 04 Sep 2019 10:05:00 AEST ]]> Experimental arthritis is dependent on mouse mast cell protease-5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34679 Trichinella spiralis-infected mice. In contrast, the constitutive HP⁺ MCs in the tongues of mMCP-5-null mice were poorly granulated and lacked mMC-CPA protein. Bone marrow-derived MCs were readily developed from the transgenic mice using IL-3. Although these MCs contained high levels of mMC-CPA mRNA, they also lacked the latter exopeptidase. mMCP-5 protein is therefore needed to target translated mMC-CPA to the secretory granule along with HP-containing serglycin proteoglycans. Alternately, mMCP-5 is needed to protect mMC-CPA from autolysis in the cell's granules. Fibronectin was identified as a target of mMCP-5, and the exocytosis ofmMCP-5from theMCs in the mouse's peritoneal cavity resulted in the expression of metalloproteinase protease-9, which has been implicated in arthritis. In support of the latter finding, experimental arthritis was markedly reduced in mMCP-5-null mice relative to wildtype mice in two disease models.]]> Wed 04 Sep 2019 09:38:57 AEST ]]> Qualitative insights into the experience of pain in older Australian women with arthritis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35751 Thu 28 Nov 2019 12:38:45 AEDT ]]> Physical examination tool for swollen and tender lower limb joints in juvenile idiopathic arthritis: a pilot diagnostic accuracy study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51747 Thu 21 Mar 2024 13:55:15 AEDT ]]> Interleukin-17 contributes to Ross River virus-induced arthritis and myositis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48937 Thu 20 Apr 2023 13:58:10 AEST ]]> Aromatase inhibitor induced musculoskeletal syndrome: a significant problem with limited treatment options https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23244 Thu 04 Nov 2021 10:39:09 AEDT ]]> Older women and arthritis: tracking impact over time https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10083 Sat 24 Mar 2018 08:12:39 AEDT ]]> Employment Status and Chronic Diseases: A Cross-sectional Study among 60-64 Year-old Men and Women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18828 Sat 24 Mar 2018 08:03:17 AEDT ]]> Incident osteoarthritis associated with increased allied health services use in 'baby boomer' Australian women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30191 Sat 24 Mar 2018 07:41:32 AEDT ]]> Cost of arthritis: a systematic review of methodologies used for direct costs https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26133 Sat 24 Mar 2018 07:41:04 AEDT ]]> Factors associated with higher healthcare costs in individuals living with arthritis: evidence from the quantile regression approach https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28167 Sat 24 Mar 2018 07:36:36 AEDT ]]> A 6-year trend of the healthcare costs of arthritis in a population-based cohort of older women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26144 Sat 24 Mar 2018 07:35:29 AEDT ]]> Prevalence of glucosamine and omega-3 fatty acid use and characteristics of users among mid-age women: analysis of a nationally representative sample of 10,638 women https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27755 Sat 24 Mar 2018 07:27:44 AEDT ]]> High chlamydia burden promotes tumor necrosis factor-dependent reactive arthritis in SKG mice https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22084 Chlamydia trachomatis is a sexually transmitted obligate intracellular pathogen that causes inflammatory reactive arthritis, spondylitis, psoriasiform dermatitis, and conjunctivitis in some individuals after genital infection. The immunologic basis for this inflammatory response in susceptible hosts is poorly understood. As ZAP-70W163C–mutant BALB/c (SKG) mice are susceptible to spondylo-arthritis after systemic exposure to microbial β-glucan, we undertook the present study to compare responses to infection with Chlamydia muridarum in SKG mice and BALB/c mice. Methods: After genital or respiratory infection with C muridarum, conjunctivitis and arthritis were assessed clinically, and eye, skin, and joint specimens were analyzed histologically. Chlamydial major outer membrane protein antigen–specific responses were assessed in splenocytes. Treg cells were depleted from FoxP3-DTR BALB/c or SKG mice, and chlamydial DNA was quantified by polymerase chain reaction. Results: Five weeks after vaginal infection with live C muridarum, arthritis, spondylitis, and psoriasiform dermatitis developed in female SKG mice, but not in BALB/c mice. Inflammatory bowel disease did not occur in mice of either strain. The severity of inflammatory disease was correlated with C muridarum inoculum size and vaginal burden postinoculation. Treatment with combination antibiotics starting 1 day postinoculation prevented disease. Chlamydial antigen was present in macrophages and spread from the infection site to lymphoid organs and peripheral tissue. In response to chlamydial antigen, production of interferon-γ and interleukin-17 was impaired in T cells from SKG mice but tumor necrosis factor (TNF) responses were exaggerated, compared to findings in T cells from BALB/c mice. Unlike previous observations in arthritis triggered by β-glucan, no autoantibodies developed. Accelerated disease triggered by depletion of Treg cells was TNF dependent. Conclusion: In the susceptible SKG strain, Chlamydia-induced reactive arthritis develops as a result of deficient intracellular pathogen control, with antigen-specific TNF production upon dissemination of antigen, and TNF-dependent inflammatory disease.]]> Mon 06 Aug 2018 11:11:21 AEST ]]> Factors associated with the health care cost in older Australian women with arthritis: an application of the Andersen's Behavioural Model of Health Services Use https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24367 Fri 22 Apr 2022 10:19:59 AEST ]]> Outcomes of paediatric septic arthritis of the hip and knee at 1-20 years in an Australian urban centre https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49158 Fri 05 May 2023 12:41:55 AEST ]]> Arthritis and tenosynovitis associated with the Anti-PD1 antibody pembrolizumab in metastatic melanoma https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24025 Fri 04 Nov 2016 13:09:47 AEDT ]]>